![]() This could have great implications for psychiatry, and helping patients overcome conditions such as depression.” “For the first time we can really see what’s happening in the brain during the psychedelic state, and can better understand why LSD had such a profound impact on self-awareness in users and on music and art. ![]() “Scientists have waited 50 years for this moment – the revealing of how LSD alters our brain biology,” Nutt said. Professor David Nutt, former chairman of the UK Advisory Council on the Misuse of Drugs and senior researcher on the study, has long argued for more research into how psychedelics affect the brain and how they could be put to medical uses. This experience is sometimes framed in a religious or spiritual way – and seems to be associated with improvements in well-being after the drug’s effects have subsided.” “It is also related to what people sometimes call ‘ego-dissolution,’ which means the normal sense of self is broken down and replaced by a sense of reconnection with themselves, others and the natural world. “Our results suggest that this effect underlies the profound altered state of consciousness that people often describe during an LSD experience,” Carhart-Harris added. READ: Why your brain works against your best intentions The visual cortex became much more active with the rest of the brain, and blood flow to visual regions also increased, which the researchers believe correlates with the hallucinations reported by volunteers. Robin Carhart-Harris, from the Department of Medicine at Imperial, who led the study. “We see this explosion of communication,” said Dr. ![]() Images of the brain under a hallucinogenic state showed almost the entire organ lit up with activity.
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